Amon L. Scoville started out as a Druggist with F.D. Hill & Co. in 1849. In 1853, he had started his own company: A.L. Scoville & Co., Patent Medicine Manufacturers. At that time O. R. Baker worked with him. Their business was located at 179 W. 4th and 60 W. 3rd Streets in Cincinnati. He started a New York branch around 1850. Initially it was at 65 Warren, and was listed on Broadway from 1850 through 1855.
Abel D. Breed was with Crane, Breed & Co. in 1859, and in 1861, he was also listed as part of A.L. Scoville & Co. The business was located from 1856 until 1865 at 12 W. 8th. In the 1865 through 67 Cincinnati Directories, Breed was listed as the Sole Proprietor of A.L. Scoville & Co., in Cincinnati.
Holcombe said that Scoville had returned to Bridgewater, Oneida County, N.Y., where he at the age of 36, resumed the practice of medicine. He said Scoville was initiated as a mason on January 15 and passed on March 19, 1863. In 1875, John F. Henry, Curran & Co., ran a full page ad in their Catalogue for Scoville's preparations including the Circassian Hair Oil and Restorative (view). According to Holcombe, Henry, Curran & Co. took over the Scoville business in 1874.
For the years 68 to 69, his name was listed only with Crane, Breed, & Co. Amon L. Scoville appeared to be connected with the business at least until 1877. From 78 on, he was listed with a home address only. A.L. Scoville & Co. issued Scoville's Farmer's & Mechanics Almanac from 1859 through 1874.